Evaluation of Salivary Glucose and Salivary Cortisol in Association with Periodontitis in People with Type II Diabetes: A Case-control Study.

BACKGROUND: The relationship between type II diabetes mellitus (DM) and periodontal disease (PD) has been discussed in recent years and may vary according to the patient's location, sex, age and family history. OBJECTIVE: In view of this possible association between periodontitis and DM, this study aimed to evaluate salivary glucose and salivary cortisol levels with periodontitis (staging and degree) in people with type II diabetes compared to non-diabetic individuals. METHODS: This was a case-control study, with 60 participants divided into two groups: DM2- people with type II diabetes (n=30) and NDM- non-diabetic individuals (n=30). For both, a clinical form and periogram were filled out, and blood samples (glycemia, glycated hemoglobin, and cortisol) and saliva (glucose and cortisol) were collected. RESULTS: The diagnosis of periodontitis was 100% in the DM2 group and 80% in the NDM group. As for staging and degree, in the DM2 group, 70% of the participants were in stage IV and 86.67% were in grade C, while in the NDM group, 58.3% of the participants were in stage I and 70.8% were in grade A. Significant differences were observed for the following variables: bleeding to probing and clinical attachment level. The laboratory data presented significant results regarding serum glucose, salivary glucose, and glycated hemoglobin. CONCLUSION: Regarding the influence of salivary glucose and cortisol on periodontal status (staging and degree), these had higher means in the DM2 group when compared to the NDM group. An association of salivary glucose and cortisol levels with the periodontal condition presented by type II diabetic individuals compared to non-diabetic individuals is suggested.

Morphological variations of the labial frenum, type of attachment and presence of diastemas: integrative review / Variações morfológicas do freio labial, tipo de inserção e presença de diastemas: revisão integrativa

ABSTRACT Objective: The aim of the present literature review was to compile data on the frequency of morphological and attachment types of the upper and lower labial frenum in different populations and investigate the association between the attachment level of the upper labial frenum and the occurrence of diastemas. Methods: Searches were conducted between May and June 2021 in the Medline (via Ovid), Google Scholar and CAPES databases. Thirty-eight studies that evaluated frenum morphology, frenum morphology and attachment or frenum morphology, attachment and the occurrence of diastemas were selected for the extraction of data. Results: Based on the data compiled in this review, the most common morphological and attachment types were labial frenum normale and mucosal attachment. The papillary and papilla penetrating types of attachment were more associated with the occurrence of diastemas. Conclusion: Longitudinal studies are needed to investigate this correlation in children and adults.

RESUMO Objetivo: O objetivo dessa revisão de literatura é compilar dados referentes a frequência de tipos morfológicos e de inserção do freio labial superior ou inferior, em diferentes populações, além de avaliar a relação entre o nível de inserção do freio labial superior e a ocorrência de diastemas. Métodos: Foram consultadas as bases de dados Medline (via Ovid), o Google acadêmico e o portal periódicos CAPES. A pesquisa foi realizada no período compreendido entre os meses de maio e junho de 2021. Foram selecionados para a extração de dados 35 estudos, que avaliação a morfologia do freio ou morfologia e inserção ou morfologia, inserção e presença de diastemas. Resultados: A partir dos dados compilados por essa revisão, foi possível estabelecer que os tipos morfológicos e de inserção mais comuns foram freio labial simples e inserção em mucosa. Com relação ao tipo de inserção e a ocorrência de diastemas, os tipos papilar e papilar penetrante foram os mais associados à sua ocorrência. Conclusão: Há necessidade de estudos longitudinais que avaliem essa correlação em crianças e populações adultas.

Maxillary Sinus Elevation Using the Bone Ring Technique with Immediate Implantation: A Case Report.

Compared to other areas of the oral cavity, an edentulous posterior maxilla poses a unique challenge for implant placement. The most important aspect to consider is the maxillary sinus. This paper describes a case in which the bone ring technique was used to raise the floor of the maxillary sinus, followed by immediate implantation. A 37-year-old woman presented with a ridge defect in the left maxilla and the absence of teeth 26 and 27 (FDI tooth-numbering system) on the same side. The treatment plan involved the extraction of tooth 25, periodontal regeneration on the distal face of tooth 24, and concomitant raising of the maxillary sinus (using the bone ring technique) with simultaneous implantation. The bone ring technique promotes bone augmentation, raises the maxillary sinus, and reduces the surgical time, surgical costs, and length of the rehabilitation period. In the case presented herein, bone tissue stability around the implants, ridge maintenance, and gingival margin stability were found at the 1-year follow-up after rehabilitation.

Treatment efficacy of gingival recession defects associated with non-carious cervical lesions: a systematic review.

PURPOSE: This systematic review aimed to compare the efficacy, defined in terms of the mean percentage of root coverage (mRC), of surgical treatment approaches combined with adhesive restorations of non-carious cervical lesions (NCCLs) to that of root coverage alone in patients with a single gingival recession (GR) and NCCL. METHODS: A literature search was conducted to identify longitudinal studies reporting the mRC following treatment for the correction of GR defects associated with NCCLs using a combination of surgical and restorative techniques in systemically and periodontally healthy patients. RESULTS: The search resulted in the retrieval of 12,409 records. Seven publications met the inclusion criteria for the qualitative synthesis of data. The mRCs ranged from 69% to 97%. In the medium term, the gingival margin position was more stable when a connective tissue graft (CTG) was used, independently of whether restoration of teeth with NCCLs was performed. CONCLUSIONS: The strength of the evidence was limited by methodological heterogeneity in terms of study design as well as the unit and period of analysis, which precluded a meta-analysis. Although no definitive conclusion could be drawn due to the lack of sufficient evidence to estimate the effectiveness of the interventions, CTG-based procedures contributed to gingival margin stability regardless of the performance of restoration to treat NCCLs.

Treatment of intrabony periodontal defects in controlled diabetic patients with an enamel matrix derivative: a split-mouth randomized clinical trial.

OBJECTIVE: This split-mouth randomized controlled trial aimed to evaluate the effect of enamel matrix derivative (EMD) associated with a simplified papilla preservation flap (SPPF) compared to SPPF alone in the surgical treatment of intrabony defects (ID) in type 2 diabetic mellitus (T2DM) patients. MATERIAL AND METHODS: Thirteen patients with controlled T2DM presenting with ID in at least two quadrants were included. In each patient, the test site (TS) was treated with SPPF plus EMD, whereas the control site (CS) was treated only with SPPF. Prior to surgery and at 6 months after intervention, the following parameters were evaluated: clinical attachment level (CAL), probing pocket depth (PPD), and gingival recession (GR). RESULTS: The TS and CS demonstrated a mean CAL gain of 3.31 ± 0.96 mm and 1.61 ± 1.12 mm, and a PPD reduction from 8.15 ± 0.98 to 3.00 ± 0.57 mm and 7.53 ± 0.96 to 4.69 ± 0.63 mm after 6 months, respectively. In both sites, the mean CAL gain and PPD reduction improved significantly after 6 months compared to baseline; however, the improvement was higher in the TS (p < 0.001). CONCLUSIONS: Both surgical procedures presented with clinical improvements in controlled T2DM patients. However, the additional use of EMD showed enhanced clinical results after 6 months with regard to CAL gain and PPD reduction. CLINICAL RELEVANCE: This study showed a better PPD reduction and CAL gain when an EMD was applied in addition to SPPF. Therefore, EMD may be used to enhance clinical outcomes in periodontal ID of controlled T2DM patients.

Facial skin injuries caused by individual protectors in the combat to covid-19 / Lesões cutâneas faciais causadas por protetores individuais no combate à covid-19

ABSTRACT The single-stranded ribonucleic acid coronavirus is the seventh known member of the Coronaviridae family to infect humans. The droplets and aerosols that are suspended in the air with the virus can be transmitted by contact with the oral, nasal and eye mucosa, which can cause severe acute respiratory syndrome. Due to the outbreak of the new coronavirus disease, the constant use of personal protective equipment by health professionals has become necessary, as the virus has a rapid and widespread spread. But, unexpectedly, the coronavirus outbreak brought another concern, the emergence of facial injuries due to the continuous and inappropriate use of these individual protectors, harming the health of these professionals. An alternative to alleviate and prevent such injuries would be the use of prophylactic creams and dressings in places where there is pressure caused by these equipment, as well as relieving the loads generated by them, at intervals that do not exceed 4 hours. Therefore, this literature review aimed to report the potential for the emergence of facial injuries caused by the continuous and inappropriate use of PPE, highlighting the most affected areas, the risks to the health of the professional, prevention and treatment, through the electronic consultation based on of data, PUBMED, SCOPUS and Bireme/BVS.

RESUMO O Coronavírus possui ácido ribonucléico de fita simples, sendo o sétimo membro conhecido da família Coronaviridae que infectam humanos. As gotículas e aerossóis que ficam suspensas no ar com o vírus pode ser transmitido por contato como mucosas bucal, nasais e oculares, podendo causar a síndrome respiratória aguda grave. Devido ao surto da nova doença do coronavírus, tornou-se necessário a utilização constante dos equipamentos de proteção individual pelos profissionais de saúde, visto que o vírus possui disseminação rápida e generalizada. Mas, inesperadamente o surto do coronavírus trouxe outra preocupação, o surgimento de lesões faciais pelo uso contínuo e inadequado destes protetores individuais, prejudicando a saúde desses profissionais. Uma alternativa para amenizar e prevenir tais lesões seria a utilização de cremes e curativos profiláticos nos locais onde há pressão causada por estes equipamentos, assim como o alivio das cargas geradas pelos mesmos, em intervalos que não ultrapassem 4 horas. Diante disso, esta revisão de literatura objetivou relatar o potencial de surgimento de lesões faciais causado pelo uso continuo e inadequado dos EPI's, evidenciando as áreas mais acometidas, os riscos à saúde do profissional, a prevenção e o tratamento, através da consulta eletrônica à base de dados, PUBMED, SCOPUS e Bireme/BVS.

Family functioning and dental trauma, malocclusion and anthropometry in adolescents

Aim: The aim of the study was to investigate perceived family cohesion and adaptability and its association with trauma, malocclusion and anthropometry in school adolescents. Methods: Cross-sectional study with a representative sample of 921 adolescents from 13 to 19 years old of both sexes, enrolled in state public schools of a northeastern Brazilian municipality. A questionnaire with sociodemographic questions, the FACES III scale was applied and a clinical oral examination (dental trauma and malocclusion) and anthropometric (BMI by age) were performed. For statistical analysis, was evaluated by the Chi-square test. The variables that presented significance in the bivariate analysis of up to 25% were taken to the multivariate analysis (multinomial logistic regression), variables that presented significance in bivariate analysis of up to 25% were taken to multivariate analysis and all conclusions were drawn considering the significance level of 5%. Results: As a result, it was identified that displaced families were associated with low maternal education, agglutinated families associated with the absence of caries. Rigid families were associated with marked overjet and caries. The prevalence of dental trauma (37.5%) was considered high. Conclusion: It was concluded that family cohesion and adaptability were associated with oral health and socioeconomic factors

Impact of tooth loss due to periodontal disease on the prognosis of rehabilitation.

When periodontal disease is diagnosed, it is difficult to predict the clinical response of treatment of a tooth over time because the result of treatment is affected by several factors and will depend on the maintenance and support of periodontal treatment. Rehabilitation with removable dental prostheses, fixed prostheses, and dental implants makes it possible to restore the function and esthetics of patients with tooth loss due to periodontal disease. The predictive factors of tooth loss in periodontitis patients should be assessed by dentists to inform their clinical decision-making during dental treatment planning. This will provide detailed individualized information and level of risk of patients considered suitable for dental rehabilitation. Therefore, the aim of this article was to review the subject of "Impact of tooth loss due to periodontal disease on the prognosis of rehabilitation" and the effect of fixed, removable, and implant-supported prostheses in periodontal patients.

Bone Ring Technique for the Treatment of Vertical and Horizontal Bone Defects with Immediate Implants: A Report of Two Cases.

In dental implant surgery, bone grafts are used for the reconstruction and reestablishment of alveolar bone volume and to improve bone architecture for better positioning of an implant. The present report describes the use of the bone ring technique for vertical and horizontal bone augmentation with simultaneous implant placement. This is a simple technique for acquiring donor bone in a ring shape and performing 3D reconstruction of bone defects, with an increase in the alveolar crest, using autogenous bone in a surgical procedure together with implant placement. Block bone grafts taken from the mentum can be used for predictable bone augmentation of up to 6 mm in the horizontal and vertical dimensions. The thickness of the bone ring collected from the mentum is very important. It cannot be too thin due to the risk of fracture, nor can it be too thick, as its contour could become deformed when placed in the receptor site. For stabilization and synthesis, a horizontal mattress suture is performed at the receptor site without promoting tension, and simple sutures are used for the complete co-optation of the flap and consequent stabilization of the clot. In the present type of bone defect, single-stage implant placement may be useful to shorten the overall treatment period.

Stress evaluation of different implant lengths on atrophic edentulous mandibles with fixed full-arch implant-supported prosthesis: a finite element analysis.

Finite element analysis was used to compare the effect of different implant lengths on atrophic mandible with full-arch fixed prostheses. Four models were constructed with different implant lengths: 4, 6, 8 and 10 mm. A 100-N occlusal load was applied. The stress at the bone level, implant, and prosthetic components were obtained. Similar behavior was observed for all groups, except for 4 mm, which showed more discrepant values ​​for all prosthetic components. Although longer implants presented better biomechanical behavior, the 4 mm implant seems to be a viable alternative for severely atrophic mandibles, however, further studies need to be carried out.

Aplicação da Tomografia de Coerência Ótica como método auxiliar de diagnóstico não invasivo na periodontia: revisão de literatura / Application of Optical Coherence Tomography as an auxiliary non-invasive diagnostic method in periodontics: literature review

O exame clínico, a sondagem periodontal e a radiografia são os três principais métodos de avaliação de saúde oral usados pelo cirurgião-dentista. Com isso, foi elaborado uma Revisão de Literatura com pesquisa no banco de dados da PubMed, Wiley Online Library e Google Acadêmico, com lapso temporal de 1998 a 2021, com o objetivo de avaliar a aplicação da TCO como possível método auxiliar no diagnóstico de doença periodontal. A partir de 1998, a TCO passa a ser estudada como possível método de diagnóstico não invasivo na Odontologia. Entre os benefícios referentes à Periodontia, tem sido relatado: a possibilidade de visualizar estruturas importantes do periodonto, fazer sondagem periodontal, diferenciar fenótipo gengival, detectar presença de cálculo supra e subgengival, além da observação de microestrutura e vascularização gengival, auxiliando no diagnóstico e acompanhamento do tratamento periodontal. Portando, a TCO é uma tecnologia emergente de bio-imagem que gera imagens estruturais bi e tridimensionais em alta resolução dos tecidos duros e moles do periodonto. Entretanto, mais estudos são necessários para superar as limitações da técnica e desenvolver sistemas de baixo custo para impulsionar seu uso em ambiente clínico... (AU)

Physical examination, periodontal probing and radiography are the three main methods of assessing oral health used by the dentist. Thereby, a Literature review was prepared based on research in the database of PubMed, Wiley Online Library and Google Academic, with time lapse from 1998 to 2021, with the objective of evaluating the application of OCT as a possible auxiliary method in the diagnosis of periodontal disease. Since 1998, the OCT has been studied as a possible non-invasive diagnostic method in Dentistry. Among the benefits related to Periodontics, it has been reported: the possibility of viewing important structures of the periodontium, periodontal probing, differentiating gingival phenotype, detecting the presence of supra and subgingival calculus, in addition to the observation of gingival microstructure and vascularization, helping in the diagnosis and monitoring of periodontal treatment. Therefore, the OCT is an emerging bio-imaging technology that generates high resolution bi and three-dimensional structural images of the hard and soft tissues of the periodontium. However, further studies are needed to overcome the limitations of the technique and develop low-cost systems to boost its use in a clinical setting... (AU)

Tratamento de mucosite periimplantar pela técnica de enxerto gengival livre: relato de caso / Treatment of peri-implant mucositis through free gingival graft technique: case report

A Mucosite peri-implantar é considerada a precursora da peri-implantite, ela é uma lesão inflamatória da mucosa peri-implantar na ausência de perda óssea marginal contínua. O objetivo desse relato de caso, foi descrever o tratamento da mucosite periimplantar através da cirurgia de enxerto gengival livre. Foi proposto, portanto, um tratamento reabilitador envolvendo uma abordagem multidisciplinar de forma a resgatar e restabelecer estética, função e bem-estar através do enxerto gengival livre para melhorar as características de mucosa e viabilizar uma previsibilidade de uma prótese definitiva implantosuportada em condições teciduais mais estáveis. O uso do EGL para aumento da gengiva queratinizada na cirurgia de implantes em paciente idosos é uma solução prática e segura para a manutenção da saúde periodontal ao redor do implante... (AU)

Peri-implant mucositis is considered the precursor of peri-implantitis, it is an inflammatory lesion of the peri-implant mucosa in the absence of continuous marginal bone loss. The purpose of this case report was to describe the treatment of peri-implant mucositis through free gingival graft surgery. Therefore, a rehabilitation treatment involving a multidisciplinary approach was proposed in order to rescue and reestablish aesthetics, function and well-being through the free gingival graft to improve the characteristics of the mucosa and enable a predictability of a permanent implant prosthesis under more stable tissue conditions. The use of EGL to increase keratinized gingiva in implant surgery in elderly patients is a practical and safe solution for maintaining periodontal health around the implant... (AU)

Hydrophilic titanium surface modulates early stages of osseointegration in osteoporosis.

OBJECTIVE: Using a mouse osteoporotic model, this study aimed to determine the influence of hydrophilic titanium surfaces on gene expression and bone formation during the osseointegration process. BACKGROUND: Based on the previous evidence, it is plausible to assume that osteoporotic bone has a different potential of bone healing. Therefore, implant surface modification study that aims at enhancing bone formation to further improve short- and long-term clinical outcomes in osteoporosis is necessary. MATERIAL AND METHODS: Fifty female, 3-month-old mice were included in this study. Osteoporosis was induced by ovariectomy (OVX, test group) in 25 mice. The further 25 mice had ovaries exposed but not removed (SHAM, control group). Seven weeks following the ovariectomy procedures, one customized implant (0.7 × 8 mm) of each surface was placed in each femur for both groups. Implants had either a hydrophobic surface (SAE) or a hydrophilic treatment surface (SAE-HD). Calcium (Ca) and phosphorus (P) content was measured by energy-dispersive X-ray spectroscopy (EDS) after 7 days. The femurs were analyzed for bone-to-implant contact (BIC) and bone volume fraction (BV) by nano-computed tomography (nano-CT) after 14 and 28 days. Same specimens were further submitted to histological analysis. Additionally, after 3 and 7 days, implants were removed and cells were collected around the implant to access gene expression profile of key osteogenic (Runx2, Alp, Sp7, Bsp, Sost, Ocn) and inflammatory genes (IL-1ß, IL-10, Tnf-α, and Nos2) by qRT-PCR assay. Statistical analysis was performed by ANOVA and paired t test with significance at P < .05. RESULTS: The amount of Ca and P deposited on the surface due to the mineralization process was higher for SAE-HD compared to SAE on the intra-group analysis. Nano-CT and histology revealed more BV and BIC for SAE-HD in SHAM and OVX groups compared to SAE. Analysis in OVX group showed that most genes (ie, ALP, Runx2) involved in the bone morphogenetic protein (BMP) signaling were significantly activated in the hydrophilic treatment. CONCLUSION: Both surfaces were able to modulate bone responses toward osteoblast differentiation. SAE-HD presented a faster response in terms of bone formation and osteogenic gene expression compared to SAE. Hydrophilic surface in situations of osteoporosis seems to provide additional benefits in the early stages of osseointegration.

Impact of tooth loss due to periodontal disease on the prognosis of rehabilitation

Abstract When periodontal disease is diagnosed, it is difficult to predict the clinical response of treatment of a tooth over time because the result of treatment is affected by several factors and will depend on the maintenance and support of periodontal treatment. Rehabilitation with removable dental prostheses, fixed prostheses, and dental implants makes it possible to restore the function and esthetics of patients with tooth loss due to periodontal disease. The predictive factors of tooth loss in periodontitis patients should be assessed by dentists to inform their clinical decision-making during dental treatment planning. This will provide detailed individualized information and level of risk of patients considered suitable for dental rehabilitation. Therefore, the aim of this article was to review the subject of "Impact of tooth loss due to periodontal disease on the prognosis of rehabilitation" and the effect of fixed, removable, and implant-supported prostheses in periodontal patients.

Chronic Periodontitis in Patients with Type 2 Diabetes: Analysis of the FokI Polymorphism and Perception of Quality of Life

Abstract Objective: To analyze whether the FokI polymorphism (rs228570) present in the vitamin D receptor gene in type 2 diabetics is related to chronic periodontitis's clinical status and evaluates the influence of chronic periodontitis on the perception of quality of life. Material and Methods: It is a clinical and laboratory study, composed of a sample of 59 individuals with previous diagnosis of type 2 Diabetes Mellitus and chronic periodontitis, of both sexes. On clinical examination, socio-epidemiological data and quality of life of patients with the Oral Health Impact Profile (OHIP-14) were recorded and a periogram was performed. Subsequently, saliva was collected spontaneously in sterile Falcon tubes (15 ml) and stored in the freezer at -20 °C. The purification of the genetic material was done with a PROMEGA kit (Wizard®), and the polymorphism studied was FokI (rs228570), found in the vitamin D receptor promoting region, with rs: 228570. After extraction of saliva DNA and purification, genotyping was performed by real-time PCR using specific allele probes (TaqMan® System). Results: The polymorphism of the vitamin D receptor gene was not positively associated with the severity and clinical characteristics of periodontitis, but suggested a relationship with the extent of the disease. Periodontitis also had no positive association with patients' perception of quality of life. Conclusion: The perception of quality of life of patients with chronic periodontitis and type 2 diabetes mellitus was compromised by the systemic condition, secondary to oral health, although some dimensions of OHIP-14 have been more frequently mentioned, such as psychological discomfort, physical pain and physical disability.

Quality of models supplied to dental laboratories for the fabrication of partial removable denture framework / Qualidade de modelos enviados aos laboratórios para execução de prótese parcialmente removível

ABSTRACT Objective The aim of this study was to evaluate the models and plannings of metallic framework of removable partial prosthesis sent to dental laboratories in the city of Recife. Methods: The physical and technical conditions of plaster models were sent by the dentists to 4 dental laboratories. All models were examined, photographed and recorded on a form according to the research objective. Results: A total number of 235 models sent by dental surgeons were used to prepare the metallic structure, in which none of the models presented surveying nor the path of insertion. Out of the 235 models, 41 (17.44%) presented serious failures, such as positive and negative bubbles, broken dental elements, direct retainers and damaged edentulous areas. With respect to the planning, only 22 (9.35%) models were presented with the metallic framework planning, but in an unsatisfactory way. Regarding mouth preparation, no model presented a guide plane, and only 6.8% of models had rests seats, but incorrectly prepared. Conclusion: The models evaluated presented poor quality, lack of planning and no mouth preparation. This shows the need for dental surgeons to be aware of the appropriate prosthesis models and plannings in order to ensure a satisfactory and long-term rehabilitation of the patient, as well as preserving the remaining mouth structures.

RESUMO Objetivo Avaliar os modelos e planejamentos das estruturas metálicas das próteses parciais removíveis enviadas aos laboratórios de prótese dentária da cidade do Recife. Métodos Foram avaliadas as condições físicas e técnicas dos modelos de gesso enviados pelos dentistas à 4 laboratórios de prótese dentária. Todos os modelos foram examinados, fotografados e registrados por meio de um formulário de acordo com o objetivo da pesquisa. Avaliou-se 235 modelos enviados pelos cirurgiões dentistas para confecção da estrutura metálica, na qual nenhum dos modelos apresentou delineamento e registro do eixo de inserção. Resultados Dos 235 modelos, 41 (17,44%) apresentaram falhas graves, tais como bolhas positivas, bolhas negativas, elementos dentários quebrados, retentores diretos e áreas edêntulas danificados. Quanto ao planejamento, apenas 22 (9,35%) modelos apresentavam-se com o desenho da estrutura metálica, porém, de maneira insatisfatória. Quanto ao preparo de boca, nenhum modelo apresentou preparo de plano guia, e apenas 6,8% dos modelos possuíam nichos, porém confeccionados de maneira incorreta. Conclusão Os modelos avaliados apresentaram qualidade insatisfatória, ausência de planejamento e realização de preparo de boca. Isto demonstra a necessidade de conscientização dos cirurgiões dentistas para a confecção dos modelos e planejamentos adequados das próteses, a fim de garantir uma reabilitação duradoura e satisfatória ao paciente, assim como proservação das estruturas bucais remanescentes.

Factors Influencing the Presence of Papilla between Adjacent Implants and between a Tooth and an Implant.

AIM: The aim this study was to evaluate the factors that influence the presence or absence of the interproximal papilla between implants adjacent to the teeth or other implants, through clinical and radiographic evaluation. MATERIAL AND METHODS: The non-probabilistic sample comprised 44 patients of both genders aged between 21 and 68 years, rehabilitated with 114 osseointegrated implants. Through a retrospective clinical study, the patients were divided according to the presence or absence of the interproximal papilla: Group 1 - Absence of Papilla, Group 2 - Partial Presence of Papilla and Group 3 - Total Presence of Papilla. The success of the implants, the periodontal biotype, and the vertical and horizontal distances of the interproximal regions included in the study were evaluated. RESULTS: Of the 114 implants, 46.5% were considered unsuccessful, and bleeding was present in 29.8%. The periodontal biotype presented as thin and scalloped was found in 85.1% of the regions. The evaluation of the groups according to the confirmation of the interproximal space showed a statistically significant difference (p = 0.007), with 61.9% of the wide and long interproximal spaces classified as Group 1, while 31% of the narrow and short interproximal spaces were classified as Group 3. CONCLUSION: It was concluded that the morphology of the interproximal space was the factor that was most strongly associated with the presence or absence of the interproximal papilla.

Polymorphisms of the vitamin D receptor gene (FOKI, CDX2, and GATA) and susceptibility to chronic periodontitis in diabetic and non-diabetic individuals: A case-control study.

AIM: The aim of the present study was to evaluate the distribution of single-nucleotide polymorphisms (SNP) (variants FOKI [rs2228570], CDX2 [rs47908762], and GATA [rs4516035]) in the vitamin D receptor in individuals with type 2 diabetes mellitus and chronic periodontitis (DM2 + CP), CP alone, and healthy individuals, and to investigate the relationship with susceptibility to CP. METHODS: In total, 280 individuals (116 with DM2 + CP, 95 with CP alone, and 69 healthy individuals) were genotyped using real-time polymerase chain reaction with allele-specific probes. Significant differences (P < .05) were found among the groups with regard to socio-epidemiological variables (sex, marital status, income, smoking habit, and schooling) and clinical-epidemiological variables (age, number of teeth, probing depth, clinical attachment loss, gingival bleeding index, and visible plaque index). RESULTS: The C allele was significantly more frequent among the healthy individuals (34.8%) than those with DM2 + CP (23.5%) (odds ratio [OR] = .58, 95% confidence interval [CI]: . 35-.94, P = .022). Likewise, the CC allele was significantly more frequent among healthy individuals (11.6%) than those with DM2 + CP (2.6%) (OR = .17, 95% CI: .03-.79, P = .015). CONCLUSION: The results suggest that the presence of these variants could lead to a lower susceptibility to DM2 and CP. No other significant differences among groups were found for the other SNP investigated.

Evaluation of oral health-related quality of life in individuals with type 2 diabetes mellitus

Aim: The aim of the present study was to evaluate the impact of oral problems on the quality of life of individuals with type 2 diabetes mellitus (DM2). Methods: A population-based, cross-sectional study was conducted with a random sample of 302 individuals with DM2 who answered the Oral Health Impact Profile 14 (OHIP-14) questionnaire as well as a questionnaire addressing socioeconomic and oral health characteristics. After filling out the questionnaires, the participants were submitted to a clinical dental examination Periodontal diseases, dental caries and edentulism. Data analysis involved descriptive statistics, bivariate analysis and logistic regression. Results: The prevalence of impact on oral health-related quality of life (OHRQoL) was 47%. In the multivariate analysis, the variables that remained significantly associated with a negative impact on quality of life were xerostomia (OR= 2.15; 95% CI: 1.07-4.30), denture need (OR= 3.71; 95% CI: 1.17-11.73) and periodontitis (OR= 5.02; 95% CI: 2.19-11.52). Conclusion: The prevalence rate of impact on OHRQoL was high in the sample studied. Xerostomia, denture need and periodontitis posed a risk of negative impact on the quality of life of individuals with DM2, independently of socioeconomic status

Oral Lichenoid Lesion Manifesting as Desquamative Gingivitis: Unlikely Association? Case Report.

INTRODUCTION: The aim of this report is to present a clinical case of oral lichenoid lesions associated with amalgam restorations with the presence of desquamative gingivitis for a nine months follow up period. CASE REPORT: The histopathologic characteristics and direct immunofluorescence were compatible with Oral Lichenoid Lesion (LLO). Diagnosis was based on a synthesis of all available information, including medical history, clinical examination, histopathology and the results of specific tests, such as the patch test, which confirmed allergy to thimerosal, an organic compound of mercury. DISCUSSION: The replacement of amalgam restorations has brought improvements to the instrument, as evidenced by the disappearance of desquamative gingivitis, aspect erythematosus and erosive lesions. The fading does not complete the same, however, indicates the need to continue has been under continuous observation, the patient, having in view the possibility of the existence of an underlying lichen planus.